How to use a key combination to send input from keyboard to a application

For Ex: how to send a key combination Alt + F1 key combination to Terminal Emulator?

You can use the below statements:

Dim WshellObjSet
WshellObj=WScript.CreateObject("WScript.Shell")
WshellObj.SendKeys "%+{F1}"

But make sure, whether QTP set context to the application before the these statements.